Synthetic liposomes are protective from bleomycin-induced lung toxicity

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Synthetic liposomes are protective from bleomycin-induced lung toxicity.

Idiopathic pulmonary fibrosis is a devastating disease characterized by a progressive, irreversible, and ultimately lethal form of lung fibrosis. Except for lung transplantation, no effective treatment options currently exist. The bleomycin animal model is one of the best studied models of lung injury and fibrosis. A previous study using mouse tumor models observed that liposome-encapsulated bl...

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ژورنال

عنوان ژورنال: American Journal of Physiology-Lung Cellular and Molecular Physiology

سال: 2011

ISSN: 1040-0605,1522-1504

DOI: 10.1152/ajplung.00149.2010