Synthetic cADPR analogues may form only one of two possible conformational diastereoisomers
نویسندگان
چکیده
منابع مشابه
Concise syntheses of trifluoromethylated cyclic and acyclic analogues of cADPR.
A novel trifluoromethylated analogue of cADPR, 8-CF3-cIDPDE (5) was designed and synthesized via construction of N1,N9-disubstituted hypoxanthine, trifluoromethylation and intramolecular condensation. A series of acyclic analogues of cADPR were also designed and synthesized. These compounds could be useful molecules for studying the structure-activity relationship of cADPR analogues and explori...
متن کاملOne Antimatter - Two Possible Thermodynamics
Conventional thermodynamics, which is formulated for our world populated by radiation and matter, can be extended to describe physical properties of antimatter in two mutually exclusive ways: CP-invariant or CPT-invariant. Here we refer to invariance of physical laws under charge (C), parity (P) and time reversal (T) transformations. While in quantum field theory CPT invariance is a theorem con...
متن کاملA Study of Two-/One-form Superfields
We study two supersymmetric toy models of a k-form superfield, k = 2, 1 separately. By “solving” Jacobi identities, we show that each model is completely solvable at offshell level, possesses a severely constrained kinematics, and gives a rigid representation of the supersymmetry algebra. This study of the toy models is motivated by our reanalysis on supersymmetry algebras in gauge theories whe...
متن کاملConformational Study of some novel Methoxy Half-Analogues of Michler’s Ketone by NMR
One series of half-analogues of Michler’s ketone containing one or more terminal methoxysubstituents with variable tertiary amino groups have been used in this study. NMR spectralresults for the parent ketones confirm earlier findings that ortho proton shifts are apparentlyindependent from steric effects in derivatives of Michler’s ketone because the ring current andcarbonyl-induced shifts are ...
متن کاملConformational studies of synthetic lipid A analogues and partial structures by infrared spectroscopy.
Synthetic lipid A analogues and partial structures were analyzed and compared with natural hexaacyl lipid A from E. coli applying Fourier transform infrared spectroscopy. The investigations comprised (i) the measurement of the beta <=> alpha phase transition of the acyl chains via monitoring of the symmetric stretching vibration of the methylene groups, (ii) an estimation of the supramolecular ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Scientific Reports
سال: 2018
ISSN: 2045-2322
DOI: 10.1038/s41598-018-33484-x