Synthesis of Substituted Benzodifuran Derivatives from Benzene Diols and α-Chloro-α-(methylthio)acetone

Synthesis of Substituted α-Trifluoromethyl Piperidinic Derivatives.

A comprehensive survey of pathways leading to the generation of α-trifluoromethyl monocyclic piperidinic derivatives is provided (65 references). These compounds have been synthesized either from 6-membered rings e.g., pipecolic acid or lactam derivatives by introduction a trifluoromethyl group, from pyridine or pyridinone derivatives by reduction, and from 5-membered rings e.g., prolinol deriv...

Synthesis and Utilization of α-Substituted Nitroxides

An efficient synthesis of α,α'-benzylidene bis(4-hydroxycoumarin) derivatives catalyzed by Tl2O3 nanoparticles

In this work, we attempted to synthesize thallium (III) oxide nano structures by direct thermal decomposition using thallium I phenylsuccinic acid coordination polymer [Tl(PsucH)]n as a precursor. Also, Tl2O3 nanoparticles have been characterized by scanning electron microscopy (SEM), X-Ray powder diffraction (XRD) and IR spectroscopy and then we report a simple and efficient method for the syn...

THE SYNTHESIS AND ANTIMICROBIAL PROPERTIES OF 4-CHLORO-2,6-BIS (2-HYDROXY- α- TOLYL) PHENOL

The synthesis of the title compound is described. This compound was found to be active (3c) against a number of pathogenic microorganisms in vitro. It is a non-absorbable antibacterial topically and its pharmacologic studies revealed that it is a non-toxic agent with a wide range of safety. It proved to be effective in the prevention and treatment of pseudomonaswound infections in voluntee...

anti-Diols from α-oxyaldehydes: synthesis and stereochemical assignment of oxylipins from Dracontium loretense.

Differentially protected 1,2-diols were synthesized by enantioselective aldehyde α-oxygenation followed by organomagnesium or -lithium addition. Contrary to a previous report, the resultant diols possess an anti configuration. Good selectivity was achieved regardless of the hybridization state of the nucleophile or the presence or absence of branching. This method was applied to short syntheses...