Synthesis of Polyhydroxylated Aminonaphthazarins Related to Natural Pigments
نویسندگان
چکیده
منابع مشابه
Stereoselective synthesis of polyhydroxylated aminocyclohexanes.
The stereoselective synthesis of a series of di- and tri-hydroxylated aminocyclohexane derivatives has been developed. A one-pot, two step tandem process involving an Overman rearrangement and a ring closing metathesis reaction has been utilised for the asymmetric synthesis of (1S)-1-(2',2',2'-trichloromethylcarbonylamino)cyclohexa-2-ene. Oxidation of this cyclohexene derivative was then studie...
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Polyhydroxylated pyrrolidine, piperidine, and indolizidine alkaloids are of great interest because of their specific glycosidase inhibitory activity." Moreover, it has recently been found in our laboratories that swainsonine (1), a representative of the polyhydroxylated indolizidine alkaloids, has an immunostimulating activity, possibly as a result of its glycosidase inhibitory activity.21 This...
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Over one hundred polyhydroxylated alkaloids have been isolated from plants and micro-organisms. These alkaloids can be potent and highly selective glycosidase inhibitors and are arousing great interest as tools to study cellular recognition and as potential therapeutic agents. However, only three of the natural products so far have been widely studied for therapeutic potential due largely to th...
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ژورنال
عنوان ژورنال: Natural Product Communications
سال: 2018
ISSN: 1934-578X,1555-9475
DOI: 10.1177/1934578x1801300217