Synthesis of phosphonate derivatives of 2′-deoxy-2′-fluorotetradialdose d-nucleosides and tetradialdose d-nucleosides

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ATTEMPTED SYNTHESIS OF 5' - DEOXY - 5' - PHOSPHONO - ISOCYTIDINE SYNTHESIS OF PHOSPHONIC ACID DERIVATIVES OF ACYCLO - NUCLEOSIDES. PREPARATION OF 1- ?- D- ARABINOFURANOSYL PYRIMIDINES

The synthesis of 5' - deoxynucleoside 5' - phosphonates which contains a 5' - CP bond in place of the 5' -COP bond of the naturally occuring nucleotides is described. The preparation of phosphonate derivatives of acyclo - nucleosides and a simple method for the conversion of 1-? -D-ribofuranosyl pyrimidines to the corresponding 1-? -D-arabinofuranosyl pyrimidines are also explained

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attempted synthesis of 5' - deoxy - 5' - phosphono - isocytidine synthesis of phosphonic acid derivatives of acyclo - nucleosides. preparation of 1- ?- d- arabinofuranosyl pyrimidines

the synthesis of 5' - deoxynucleoside 5' - phosphonates which contains a 5' - cp bond in place of the 5' -cop bond of the naturally occuring nucleotides is described. the preparation of phosphonate derivatives of acyclo - nucleosides and a simple method for the conversion of 1-? -d-ribofuranosyl pyrimidines to the corresponding 1-? -d-arabinofuranosyl pyrimidines are also ex...

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ژورنال

عنوان ژورنال: Tetrahedron

سال: 2021

ISSN: 0040-4020

DOI: 10.1016/j.tet.2021.132159