Synthesis of functional styrene derivatives-carbon monoxide copolymer
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چکیده
منابع مشابه
Synthesis of fenoprofen and gemfibrozil styrene-maleic acid copolymer conjugates.
Two types of polymer-drug conjugates were synthesized starting from styrene-maleic acid anhydride copolymer (SMA). Fenoprofen and gemfibrozil were chosen as model drugs because of their short plasma half lives. Both drugs were first converted to their 2-aminoethylamides, which possess free amino groups capable of reacting with SMA anhydride rings. By modifying the degree and type of substitutio...
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ژورنال
عنوان ژورنال: Journal of Applied Polymer Science
سال: 1998
ISSN: 0021-8995,1097-4628
DOI: 10.1002/(sici)1097-4628(19980502)68:5<855::aid-app17>3.0.co;2-p