Synthesis of deuterated dextromethorphan derivatives
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چکیده
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Spin Relaxation in Nematogensand their Deuterated Derivatives
A brief review of spin relaxation (1) in nematogens is given. The usual problems in this area arise from the lack of a good theoretical model and a spin system in which meaningful measurements and direct comparison with the model can be made. The proton and deuteron spin-lattice relaxation in nematics have been extensively studied both theoretically (2,3) and experimentally (4-8). It is general...
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A novel access to deuterated and D(3)CO-substituted arenes has been developed using immobilized triazenes as precursors. The linker system and the deuterating cleavage methodology could be shown to be compatible with various functional groups and are therefore suitable for the synthesis of derivatives only hardly available via comparable protocols.
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Since the discovery of deuterium,' there has been considerable interest in the preparation of a variety of compounds in which hydrogen has been replaced by this heavier isotope. Some of the research has centered around the synthesis of deuterated compounds for biological study.2 While not occupying a place of prominence in this work, the preparation of deuterated amino acids has been studied in...
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Human cholesterogenesis is measurable as the rate of Incorporation of deuterium derived from deuterium oxide (D2O) within the body water pool into plasma or erythrocyte cholesterol pools. Oral D2O equilibrates across body water, thus enabling extracellular sampling of pools (such as urine) to serve as accurate indicators of intracellular deuterium enrichments at the point of synthesis. Required...
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ژورنال
عنوان ژورنال: Arkivoc
سال: 2008
ISSN: 1551-7012
DOI: 10.3998/ark.5550190.0009.316