Synthesis of Compounds Related to Muscarufin. V. Ethyl 5-(5-methoxy-p-benzoquinonyl)-valerate.
نویسندگان
چکیده
منابع مشابه
Design, Synthesis and Anti-Tubercular Activity of Novel 1, 4-Dihydropyrine-3, 5-Dicarboxamide Containing 4(5)-Chloro-2-Ethyl-5(4)-Imidazolyl Moiety
Current researches have showed that N3, N5-diaryl-2, 6-dimethyl -1, 4-dihydropyrine-3, 5- dicarboxamide analogues demonstrate notable anti-tubercular activity. In this study, Hantzsch condensation was used to design and synthesize new analogues of dihydropyridine (DHP). Different diary carboxamides were inserted at positions 3 and 5 of the DHP ring. 4(5)-chloro-2-ethyl-5(4)-imidazolyl moiety wa...
متن کاملSimultaneous Determination of V (V) and Co (II) as (S)-5- Methoxy-2-[[(4-Methoxy-3, 5-Dimethyl-2-Pyridinyle-Methyle] Sulfinyle]-1H-Benzimidazole Using Derivative Spectrophotometry
The reagent (S)-5-methoxy-2-[[(4-methoxy-3, 5-dimethyl-2-pyridinyle-methyle] sulfinyle]-1H-benzimidazole gives greenish yellow coloration with V (V) as well as Co (II) in basic medium. This observation is used for the simultaneous determination of both the metal ions using Zero and second order derivative spectrophotometry. Optimum conditions were established for this determination. Job’s and m...
متن کاملDesign, Synthesis and Anti-Tubercular Activity of Novel 1, 4-Dihydropyrine-3, 5-Dicarboxamide Containing 4(5)-Chloro-2-Ethyl-5(4)-Imidazolyl Moiety
Current researches have showed that N3, N5-diaryl-2, 6-dimethyl -1, 4-dihydropyrine-3, 5- dicarboxamide analogues demonstrate notable anti-tubercular activity. In this study, Hantzsch condensation was used to design and synthesize new analogues of dihydropyridine (DHP). Different diary carboxamides were inserted at positions 3 and 5 of the DHP ring. 4(5)-chloro-2-ethyl-5(4)-imidazolyl moiety wa...
متن کاملEvaluation of (5R,6R)-5-Bromo-6-Ethoxy-5-Ethyl-5,6-Dihydro-2\'- Deoxyuridine as a Brain-Targeted Prodrug of 5-Ethyl-2\'- Deoxyuridine
(+)-Trans-(5R,6R)-5-bromo-6-ethoxy-5-ethyl-5,6-dihydro-2'-deoxyuridine [(5R,6R)-BEEDU], a potential brain-targeted prodrug of 5-ethyl-2'-deoxyuridine (EDU), was synthesized by the regiospecific addition of BrOEt to the 5,6-olefinic bond of EDU. (5R,6R)-BEEDU is more lipophilic (log P = 0.04) than EDU (log P = -1.09). In vitro incubation of (5R,6R)-BEEDU with rat whole blood and brain homogena...
متن کاملFour-Component Reaction between Ethyl Benzoylacetate, Hydroxylamine, Aldehydes and Malononitrile: Synthesis of Isoxazol-5(2H)-Ones
We present herein a new and efficient four-component synthesis of isoxazol-5(2H)-ones involving ring closing/Knoevenagel condensation/Michael addition sequential reactions.
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ژورنال
عنوان ژورنال: Acta Chemica Scandinavica
سال: 1960
ISSN: 0904-213X
DOI: 10.3891/acta.chem.scand.14-2243