Synthesis of Bacterial 2-Alkyl-4(1H)-quinolone Derivatives
نویسندگان
چکیده
منابع مشابه
Isoquinoline Promoted Synthesis of alkyl 2-(1-alkyl-5-oxo-3-phenyl-2-thioxotetrahydro-4H-imidazol-4-yliden) acetate derivatives
Derivatives of thiazolidinone ring systems are known to act as anti-HIV infections , analgesic, anti-bacterial, anti-convulsant, anti parasitic, potential anti-inflammatory and herbicidal agents. Due biological activities of thiazolidinones ring, several methods for their synthesis have been illustrated in literature. Imidazolidine-2-thiones were synthesized by the oxidative cyclization of 1-be...
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Reaction of 4-hydroxy-7-methoxy-2(lH)-quinolone (1) with iodosobenzenes, prepared in situ from the dichloroiodo compounds 2a,b, afforded the iodoniumylides 3a,b in good yields. Their thermal rearrangement produced the 3-iodo-4-aryloxy-quinolones 4a,b. Reductive -deiodinatton of 4a,b gave the corresponding arylethers 5a,b. By photocyclization 4a as well as 5a yielded the benzofuro-quinolone 6a (...
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A new series of 2-(5-nitro-2-heteroaryl)-1,3,4-thiadiazole derivatives, including nitro furan, nitro thiophene and nitro imidazole, were synthesized and screened in vitro for their inhibitory activity against eight bacterial strains. The results showed that most of the synthesized compounds were active against Gram-positive bacteria, determined by MIC method. Among them, compounds <str...
متن کاملisoquinoline promoted synthesis of alkyl 2-(1-alkyl-5-oxo-3-phenyl-2-thioxotetrahydro-4h-imidazol-4-yliden) acetate derivatives
derivatives of thiazolidinone ring systems are known to act as anti-hiv infections , analgesic, anti-bacterial, anti-convulsant, anti parasitic, potential anti-inflammatory and herbicidal agents. due biological activities of thiazolidinones ring, several methods for their synthesis have been illustrated in literature. imidazolidine-2-thiones were synthesized by the oxidative cyclization of 1-be...
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Optically pure conjugates of quinolone antibiotics with naturally occurring amino acids are synthesized in 40-98% yields.
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ژورنال
عنوان ژورنال: Arkivoc
سال: 2021
ISSN: ['1551-7012', '1551-7004']
DOI: https://doi.org/10.24820/ark.5550190.p011.547