Synthesis and Evaluation of a Thermoresponsive Degradable Chitosan-Grafted PNIPAAm Hydrogel as a “Smart” Gene Delivery System
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منابع مشابه
Preparation and in vitro evaluation of a novel chitosan-based hydrogel for injectable delivery of enrofloxacin
BACKGROUND: The development of injectable sustained-release products are of great interest to veterinary pharmaceuticals and animal health business. Recently, great attention has been paid to in situ gel-forming chitosan/beta-glycerophosphate (chitosan/β-GP) solutions due to their good biodegradability and thermosensitivity. OBJECTIVES: The general aim of this study was to prepare a novel in si...
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Chitosan obtained by alkaline deacetylation of chitin is a non-toxic, biocompatible, and biodegradable natural polymer. Chitosan-based hydrogel polymeric beads have been extensively studied as microor nano-particulate carriers in the pharmaceutical and medical fields, where they have shown promise for drug delivery as a result of their controlled and sustained release properties, as well as bio...
متن کاملpreparation and in vitro evaluation of a novel chitosan-based hydrogel for injectable delivery of enrofloxacin
background: the development of injectable sustained-release products are of great interest to veterinary pharmaceuticals and animal health business. recently, great attention has been paid to in situ gel-forming chitosan/beta-glycerophosphate (chitosan/β-gp) solutions due to their good biodegradability and thermosensitivity. objectives: the general aim of this study was to prepare a novel in si...
متن کاملChitosan Loaded into a Hydrogel Delivery System as a Strategy to Treat Vaginal Co-Infection
Polymeric hydrogels are common dosage forms designed for the topical administration of antimicrobial drugs to treat vaginal infections. One of the major advantages of using chitosan in these formulations is related to the intrinsic and broad antimicrobial activity exerted on bacteria and fungi by this natural polymer. Most vaginal yeast infections are caused by the pathogenic fungus Candida alb...
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ژورنال
عنوان ژورنال: Materials
سال: 2020
ISSN: 1996-1944
DOI: 10.3390/ma13112530