Synthesis and Biological Screening of 4-Benzyl-2H-phthalazine Derivatives
نویسندگان
چکیده
منابع مشابه
Synthesis and Biological Screening of 4-Benzyl-2H-phthalazine Derivatives
Preparation of 4-benzyl-2-substituted phthalazin-1-one derivatives 2-8 is reported. Condensation of 4-benzyl-1-chlorophthalazine (9) with a series of different nucleophiles gave 4-benzylphthalazin-1-ylamino derivatives (10-13 and 16) and 4-amino-2-[N'-(4-benzylphthalazin-1-yl)-hydrazino]-6-arylpyrimidine-5-carbonitriles (14a,b). Interaction of 9 with ambident anions was also studied. 5-Benzyl-6...
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ژورنال
عنوان ژورنال: Pharmaceuticals
سال: 2011
ISSN: 1424-8247
DOI: 10.3390/ph4081158