Synthesis and Bioactivity of Hydrazide-Hydrazones with the 1-Adamantyl-Carbonyl Moiety
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چکیده
منابع مشابه
Hydrazide-Hydrazones in the Synthesis of 1,3,4-Oxadiazine, 1,2,4-Triazine and Pyrazole Derivatives with Antitumor Activities
The reaction of cyanoacetyl hydrazine (1) with the -haloketones 2a-2c in 1,4-dioxane afforded the hydrazidehydrazone derivatives 3a-3c. The latter products were used in a series of heterocyclization to give 1,3,4-oxadiazine, 1,2,4triazine and pyrazole derivatives. All compounds synthesized through this work are new products and their antitumor evaluation towards three human tumor cell lines rep...
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15 صفحه اولsingle-step synthesis of multi-component spirobarbiturates using ionic liquids and synthesis of substituted pyridine filled with catalysts supported on solid substrate
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15 صفحه اولSynthesis of benzaldehyde substituted phenyl carbonyl hydrazones and their formylation using Vilsmeier-Haack reaction
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Identification of the novel (E)-N'-((2-chloro-7-methoxyquinolin-3-yl)methylene)-3-(phenylthio)propanehydrazide scaffold 18 has led to the development of a new series of biologically active hydrazide compounds. The parent compound 18 and new quinoline derivatives 19-26 were prepared from the corresponding quinoline hydrazones and substituted carboxylic acids using EDC-mediated peptide coupling r...
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ژورنال
عنوان ژورنال: Molecules
سال: 2019
ISSN: 1420-3049
DOI: 10.3390/molecules24214000