Synthesis and Antiproliferative Effect of Novel Curcumin Analogues
نویسندگان
چکیده
منابع مشابه
Synthesis and antiproliferative effect of novel curcumin analogues.
Novel curcumin analogues with α,β-unsaturated ketone moiety and/or α,β-saturated ketone structure were synthesized from curcumin via alkylation at the central carbon and the phenolic hydroxy groups, and hydrogenation of α,β-unsaturated ketone moiety. The antiproliferative activities were tested in five human solid tumor cell lines in vitro. Most of the compounds exhibited increased antiprolifer...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 2013
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.c13-00295