SYNTHESIS AND ANTI INFLAMMATORY ACTIVITY OF 3,5- DIPHENYL 4-AMINO 1,2,4 -TRIAZOLE DERIVATIVES
نویسندگان
چکیده
منابع مشابه
Synthesis and Anti-Inflammatory Activity of New Alkyl-Substituted Phthalimide 1H-1,2,3-Triazole Derivatives
Four new 1,2,3-triazole phthalimide derivatives with a potent anti-inflammatory activity have been synthesized in the good yields by the 1,3-dipolar cycloaddition reaction from N-(azido-alkyl)phthalimides and terminal alkynes. The anti-inflammatory activity was determined by injecting carrageenan through the plantar tissue of the right hind paw of Swiss white mice to produce inflammation. All t...
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متن کاملSynthesis of some novel triazole derivatives as anti-nociceptive and anti-inflammatory agents.
Eight novel 1-[2-(1H-tetrazol-5-yl)ethyl]-1H-benzo[d][1,2,3]triazoles (3a-h) have been synthesized in order to obtain new compounds with potential anti-nociceptive and anti-inflammatory activity. The titled compounds were synthesized by the condensation of 1-[2-(1H-tetrazol-5-yl) ethyl]-1H-benzotriazole (2) and appropriate acid chlorides. Compound 2 was synthesized by reacting 3-(1H-benzo[d][1,...
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ژورنال
عنوان ژورنال: World Journal of Pharmaceutical Research
سال: 2017
ISSN: 2277-7105
DOI: 10.20959/wjpr20178-9073