Syngeneic AAV Pseudo-particles Potentiate Gene Transduction of AAV Vectors
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چکیده
منابع مشابه
Syngeneic AAV Pseudo-particles Potentiate Gene Transduction of AAV Vectors
Adeno-associated virus (AAV) vectors have emerged as a safe and efficient gene therapy platform. One complication is that a significant amount of empty particles have always been generated as impurities during AAV vector production. However, the effects of such particles on AAV vector performance remain unclear. Here we systemically evaluated the biological properties of three types of "empty" ...
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ژورنال
عنوان ژورنال: Molecular Therapy - Methods & Clinical Development
سال: 2017
ISSN: 2329-0501
DOI: 10.1016/j.omtm.2016.12.004