Synergism of Antifungal Activity between Mitochondrial Respiration Inhibitors and Kojic Acid
نویسندگان
چکیده
منابع مشابه
Synergism of antifungal activity between mitochondrial respiration inhibitors and kojic acid.
Co-application of certain types of compounds to conventional antimicrobial drugs can enhance the efficacy of the drugs through a process termed chemosensitization. We show that kojic acid (KA), a natural pyrone, is a potent chemosensitizing agent of complex III inhibitors disrupting the mitochondrial respiratory chain in fungi. Addition of KA greatly lowered the minimum inhibitory concentration...
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ژورنال
عنوان ژورنال: Molecules
سال: 2013
ISSN: 1420-3049
DOI: 10.3390/molecules18021564