Suzanne Pfeffer: Sorting through membrane trafficking
نویسندگان
چکیده
منابع مشابه
Suzanne Pfeffer: Sorting through membrane trafficking
S uzanne Pfeffer always wanted to know what makes the human body tick. In many respects, we're still working on deciphering the fi rst page of the body's operating manual—which Pfeffer says is fi ne, since it means there's plenty of room for new discoveries. Pfeffer had her fi rst publication as an undergraduate at UC Berkeley (1), which got her hooked on the spirit of scientifi c inquiry. Foll...
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The Pfeffer Zelle (Pfeffer Cell Apparatus), invented by Wilhelm Pfeffer [6] in 1877, measured the minimum pressure needed to prevent a pure solvent from passing into a solution across a semi-permeable membrane, called osmotic pressure. The apparatus provided Pfeffer with a way to quantitatively measure osmotic pressure. Pfeffer devised the apparatus in the 1870s at the University of Basel [7] i...
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Glycogen synthase kinase β (GSK3β) phosphorylates many substrates in mammalian cells, and functions in many physiological processes. We observed that GSK3β knockdown by siRNA perturbed both Golgi morphology in HeLa cells and the anterograde transport of cation-independent mannose 6-phosphate receptor (CI-M6PR) from the trans-Golgi network (TGN) to prelysosomal compartments (PLC), diverting it t...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2009
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.1851pi