SUXAMETHONIUM-SENSITIVE GENOTYPES

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Goodbye suxamethonium!

No drugs in anaesthesia are more problematic than suxamethonium. Yet, no drugs have survived as suxamethonium does in spite of crisis after crisis, and attempt after attempt at its replacement. For decades, suxamethonium has taught us neuromuscular pharmacology and provided us with an encyclopaedia of side effects, while benefiting millions and millions of our anaesthetised patients. With the a...

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Suxamethonium-induced myalgia.

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Cholinesterase unit establishment and issuing of >>Warning Cards<< for carriers of suxamethonium sensitive serum butyrylcholinesterase variants.

Recognition of butyrylcholinesterase (EC 3.1.1.8) variants in human serum is essential to identify patients who may be susceptible to a prolonged reaction of suxamethonium and mivacurium, short-acting muscle relaxants. Thus they can be given appropriate advice along with their relatives who may be similarly affected. Therefore, Cholinesterase Unit for detection of individuals, carriers of inher...

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Hexafluorenium extension of suxamethonium block.

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ژورنال

عنوان ژورنال: British Journal of Anaesthesia

سال: 1988

ISSN: 0007-0912

DOI: 10.1093/bja/60.7.866