Survival Quantitative Trait Locus Fine Mapping by Measuring and Testing for Hardy–Weinberg and Linkage Disequilibrium
نویسندگان
چکیده
منابع مشابه
Survival quantitative trait locus fine mapping by measuring and testing for Hardy-Weinberg and linkage disequilibrium.
I show that fine-scale localization of a survival-related locus can be accomplished on the basis of deviations from Hardy-Weinberg equilibrium and linkage disequilibrium at closely linked marker loci. The method is based on chi(2)-tests and they can be performed for age-specific samples of alive (or dead) individuals, as for combined samples of alive and dead individuals.
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ژورنال
عنوان ژورنال: Genetics
سال: 2007
ISSN: 1943-2631
DOI: 10.1534/genetics.106.067264