Survival after induction chemotherapy in locoregional advanced nasopharyngeal carcinoma: An updated systematic review and meta‐analysis

نویسندگان

چکیده

Abstract Background Induction chemotherapy (ICT) augmentation is a common strategy for standard concurrent chemoradiotherapy (CCRT) of locoregionally advanced nasopharyngeal carcinoma (NPC). The survival condition crucial issue patients with NPC. ICT CCRT treatment versus alone should be elucidated via systemic review and meta‐analysis randomized clinical trials. Methods We compared to determine if can associated significant benefit conditions CCRT. Different indicators were analyzed the Twelve studies total 3711 NPC enrolled. focused outcome was overall survival, progression‐free distant metastasis‐free locoregional recurrence‐free survival. Results Our results showed that status treatment. Similar benefits in seen Conclusions updated suggest might overall, progression‐free, metastasis‐free, as well dimensions However, bias different kinds, doses, regimens agents radiotherapy not ignored.

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ژورنال

عنوان ژورنال: Laryngoscope investigative otolaryngology

سال: 2023

ISSN: ['2378-8038']

DOI: https://doi.org/10.1002/lio2.1133