Surgical Periodontal Therapy with Recombinant Human Fibroblast Growth Factor-2 in Treatment of Chronic Periodontitis: A Case Report with 2-year Follow-up

We report a case of generalized chronic periodontitis requiring periodontal regenerative therapy. The patient was 53-year-old woman who presented with the chief complaint gingival swelling. An initial examination revealed 31.5% sites probing depth ≥4 mm and 46.3% bleeding on probing. Radiographic showed vertical bone resorption in tooth #33. Horizontal adsorption also observed other areas. Based clinical diagnosis severe periodontitis, therapy consisting plaque control, scaling root planing, occlusal adjustment, caries treatment, splint placement performed. After re-evaluation, surgical treatment performed at selected sites. Periodontal regeneration recombinant human fibroblast growth factor (rhFGF)-2 Two (#14, 15), which had residual pockets, were treated by open-flap debridement. placed maintenance program. rhFGF-2 resulted an improvement angular resorption, has been properly maintained for 2 years. Continued care is needed to maintain stable conditions.