Surfactant Therapy in Severe Meconium Aspiration Syndrome
نویسندگان
چکیده
منابع مشابه
Meconium aspiration syndrome in neonates
Perhaps the most significant changes in airway management over the recent years have been in the management of an infant delivered through meconium- stained amniotic fluid( MSAF). MSAF occurs in approximately 10℅ to 20℅ of all deliveries and increases to over 30℅ in deliveries after 42 weeks gestation. Meconium aspiration syndrome ( MAS) occurs in about 2℅ to 5℅ of these cases with a high morta...
متن کاملN-acetylcysteine advancement of surfactant therapy in experimental meconium aspiration syndrome: possible mechanisms.
Meconium aspiration syndrome (MAS) is meconium-induced respiratory failure of newborns associated with activation of inflammatory and oxidative pathways. For severe MAS, exogenous surfactant treatment is used which improves respiratory functions but does not treat the inflammation. Oxidative process can lead to later surfactant inactivation; hence, surfactant combination with antioxidative agen...
متن کاملMeconium aspiration syndrome.
In the years 1977-82, 43 infants with the meconium aspiration syndrome (MAS) were managed at the Department of Paediatrics of Turku University Central Hospital (TUCH), Finland. Among 5,353 deliveries in one year the incidence of meconium staining was 8.7%. By extrapolation, the incidence of meconium aspiration in all newborns is approximately 0.13%. The mean duration of the pregnancies was 39.2...
متن کاملMeconium aspiration syndrome.
We agree that the passage of meconium in utero is not always due to intrauterine asphyxia and it may be a purely physiological event due to increasing maturity of the fetus. However, a bacterial endotoxin has been recently implicated in "causing the preterm labor and passage of meconium in utero(3). It is to be emphasized that only those neonates who have respiratory\distress with radiological ...
متن کاملSurfactant lavage therapy for meconium aspiration syndrome: a systematic review and meta-analysis.
BACKGROUND Lung lavage with diluted surfactant has emerged as an innovative treatment for meconium aspiration syndrome (MAS). However, the treatment effect has not yet been fully established. OBJECTIVE To investigate the effects of surfactant lavage therapy for MAS by a systematic meta-analysis. METHODS Relevant studies were identified by database searches in MEDLINE (from 1950), EMBASE (fr...
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ژورنال
عنوان ژورنال: Neonatal Medicine
سال: 2013
ISSN: 2287-9412,2287-9803
DOI: 10.5385/nm.2013.20.3.318