Surface Modification of Gelatin Nanoparticles with Polyethylenimine as Gene Vector
نویسندگان
چکیده
منابع مشابه
Brevinin-2R-linked polyethylenimine as a promising hybrid nano-gene-delivery vector
Objective(s): Polyethylenimine (PEI) is one of the most widely used polymers in gene delivery. The aim of this study was to modify PEI by replacing some of its primary amines with Brevinin 2R (BR-2R) peptide in order to increase the efficiency of gene delivery.Materials and Methods: Polyethylenimine was modified by BR-2R peptide by two d...
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An excellent gene vector is of great importance for the development of the gene therapy. Gelatin–siloxane nanoparticles (GS NPs) with controlled size and surface charge were synthesized through a two-step sol–gel process for gene vector. In order to increase the efficiency of tumour targeting, HIV-derived Tat peptide and TTA1, a kind of modified RNA aptamer, were further grafted onto GS NPs (GS...
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Vaccines have shown great success in treating and preventing tumors and infections, while adjuvants are always demanded to ensure potent immune responses. Polyethylenimine (PEI), as one of the well-studied cationic polymers, has been used as a transfection reagent for decades. However, increasing evidence has shown that PEI-based particles are also capable of acting as adjuvants. In this paper,...
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in this thesis our aim is to construct vector field in r3 for which the corresponding one-dimensional maps have certain discontinuities. two kinds of vector fields are considered, the first the lorenz vector field, and the second originally introced here. the latter have chaotic behavior and motivate a class of one-parameter families of maps which have positive lyapunov exponents for an open in...
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ژورنال
عنوان ژورنال: Journal of Nanomaterials
سال: 2011
ISSN: 1687-4110,1687-4129
DOI: 10.1155/2011/646538