Surface Charge of Streptococcus pneumoniae Predicts Serotype Distribution

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Surface charge of Streptococcus pneumoniae predicts serotype distribution.

Streptococcus pneumoniae (pneumococcus) frequently colonizes the human nasopharynx and is an important cause of pneumonia, meningitis, sinusitis, and otitis media. The outer cell surface of pneumococcus may assume various degrees of negative charge depending on the polysaccharide capsule, of which more than 90 serotypes have been identified. The negative charge of capsular polysaccharides has b...

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ژورنال

عنوان ژورنال: Infection and Immunity

سال: 2013

ISSN: 0019-9567,1098-5522

DOI: 10.1128/iai.00724-13