Suppression of microRNAs by dual-targeting and clustered Tough Decoy inhibitors
نویسندگان
چکیده
منابع مشابه
Potent microRNA suppression by RNA Pol II-transcribed 'Tough Decoy' inhibitors.
MicroRNAs (miRNAs) are key regulators of gene expression and modulators of diverse biological pathways. Analyses of miRNA function as well as therapeutic managing of miRNAs rely on cellular administration of miRNA inhibitors which may be achieved by the use of viral vehicles. This study explores the miRNA-suppressive capacity of inhibitors expressed intracellularly from lentivirus-derived gene ...
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ژورنال
عنوان ژورنال: RNA Biology
سال: 2013
ISSN: 1547-6286,1555-8584
DOI: 10.4161/rna.23543