SUN-LB100 False Elevation of Thyroglobulin by Immunoassay with Negative Thyroglobulin Antibody and Measures Blocking Heterophile Antibody in a Patient Post-thyroidectomy for Papillary Thyroid Cancer; Use of Liquid Chromatography─Tandem Mass Spectrometry
نویسندگان
چکیده
منابع مشابه
Changes in serum thyroglobulin antibody levels as a dynamic prognostic factor for early-phase recurrence of thyroglobulin antibody-positive papillary thyroid carcinoma after total thyroidectomy.
We demonstrated previously that dynamic prognostic markers such as the thyroglobulin (Tg)-doubling time in thyroglobulin antibody (TgAb)-negative papillary thyroid carcinoma (PTC) and changes in pre- and postoperative TgAb levels in TgAb-positive PTC patients more keenly reflect patients' prognosis than conventional static prognostic factors. Here we investigated periodic changes in TgAb levels...
متن کاملRecurrence of papillary thyroid cancer suspected by high anti-thyroglobulin antibody levels and detection of peripheral blood thyroglobulin mRNA.
The amplification of thyroglobulin (TG) mRNA in peripheral blood of patients with thyroid cancer has been studied for almost one decade, but its real contribution for diagnosis of cancer relapse has not yet been established. In the present paper we report the case of a patient with papillary thyroid cancer with undetectable stimulated serum thyrogobulin levels after thyroid ablation. Follow-up ...
متن کاملA comparison of tests for thyroglobulin antibody.
A comparison is made of tests for thyroglobulin antibody, using gel diffusion, electroprecipitin, bentonite flocculation, tanned red cell agglutination, and latex slide agglutination techniques on sera from cases of Hashimoto's disease and other thyroid disorders. Any increase in gamma globulin was also noted from the serum electrophoretic pattern. The gel diffusion and electroprecipitin tests ...
متن کاملImplications of thyroglobulin antibody positivity in patients with differentiated thyroid cancer: a clinical position statement.
BACKGROUND Even though the presence of antithyroglobulin antibodies (TgAbs) represents a significant problem in the follow-up of patients with differentiated thyroid cancer (DTC), the current guidelines on the management of DTC that have been published in recent years contain no text concerning the methods to be used for detecting such antibody-related interference in thyroglobulin (Tg) measure...
متن کاملSerum Thyroglobulin Measurement by Mass Spectrometry in the Follow-Up of Thyroid Cancer Patients
6 Asymptomatic Paget’s Disease — To Treat or Not to Treat Throughout most of the 20th century, thyroid carcinoma was considered a rare cancer with a low death rate. During the last 20 to 25 years, however, incidence rates of thyroid cancer have risen exponentially across the world. In combination with the low cause-specific mortality rate of thyroid cancer, this increase has led to huge numbers...
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ژورنال
عنوان ژورنال: Journal of the Endocrine Society
سال: 2019
ISSN: 2472-1972
DOI: 10.1210/js.2019-sun-lb100