Sulfadiazine Susceptibility Patterns of Neissera meningitidis Group Y

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Susceptibility of Neisseria meningitidis strains from the civilian population to sulfadiazine, penicillin, and rifampin.

The minimal inhibitory concentration (MIC) values of sulfadiazine, penicillin, and rifampin for meningococcal strains isolated from civilians during 1970 were compared. The strains were isolated from various sources and geographical areas and represented several serogroups. The ranges of MIC values were as follows: 0.05 to 20 mg/100 ml for sulfadiazine, 0.01 to 0.4 mug/ml for penicillin, and 0....

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Epitope specificities of the group Y and W-135 polysaccharides of Neisseria meningitidis.

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Comparison of susceptibility of Neisseria meningitidis

When prevalence of meningococcal disease is increased contacts of cases may require chemoprophylaxis, and sodium sulphadiazine is the drug of choice. However, increasing numbers of meningococci are resistant to sulphonamides (Fallon, 1975, 1977) andmany alternative chemoprophylactic agents are ineffectual. Sodium fusidate is active against a few strains of meningococci in vitro (Barber and Wate...

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In vitro susceptibility of Neisseria meningitidis.

Sir, Reduced susceptibility of Neisseria meningitidis to penicillin (MICs 0.12 mg/L) in the UK was reported by Jones & Sutcliffe in 1990 to be at a level of 3%, comparable to that found in 1987. We have recently undertaken an in vitro study to investigate the susceptibility of meningococci from our collection of strains, to a variety of antimicrobial agents, including penicillin, using BSAC met...

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Invasive Neisseria meningitidis infection is rare but carries a high mortality rate. The carriage rate in the normal population is around 10% and can be higher in confined populations. A study on the prevalence of carriage of N. meningitidis was conducted among 3195 army recruits after 2 months of intensive training in an army camp. N. meningitidis was isolated from 37.0% of these recruits. Two...

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ژورنال

عنوان ژورنال: Applied Microbiology

سال: 1969

ISSN: 0003-6919

DOI: 10.1128/aem.18.6.1091-1091.1969