Succinylcholine apnoea: Attempted reversal with anticholinesterases
نویسندگان
چکیده
منابع مشابه
Prolonged Apnoea with Succinylcholine during Electro-convulsive Therapy
Electro-convulsive therapy (ECT) is one of the important treatment modality for psychiatric patients, particularly in developing countries like India. The introduction of curare and subsequently succinylcholine chloride (Holmerg and Thesleff 1952) as an important adjunct in the administration of ECT, was a major advance in reducing the morbidity associated with ECT. The relative safety of succi...
متن کاملThe use of serum cholinesterase in succinylcholine apnoea.
Fifteen patients demonstrating unexpected prolonged apnoea lasting several hours after succinylcholine have been treated by a new preparation of human serum cholinesterase. Adequate spontaneous respiration was re-established in an average period of ten minutes after the injection. In 12 patients biochemical genetic examinations confirmed the presence of an atypical serum cholinesterase. In thre...
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BACKGROUND Concerns about the safety of paralytics such as succinylcholine to facilitate endotracheal intubation limit their use in prehospital and emergency department settings. The ability to rapidly reverse paralysis and restore respiratory drive would increase the safety margin of an agent, thus permitting the pursuit of alternative intubation strategies. In particular, patients who carry g...
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The significance of new findings in two areas will be discussed with respect to the design of inhibitors of acetylcholinesterase. One area is that of enzyme structure, including the oligomeric form and the existence of allosteric binding sites, of isozymes and of a mutant enzyme. The other area is that of the forces which bind inhibitors to the enzyme prior to reacting with it, including ionic,...
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4.5. Bisbenzyl-isoquinolinium compounds 4.5.2. Mivacurium 4.6. Reversal of non-depolarizing neuromuscular block by anticholinesterases 4.7. Other neuromuscular uses of anticholinesterases 4.8. Pharmacokinetics of non-depolarizing neuromuscular blocking drugs 4.8.1 Clearance of non-depolarizing neuromuscular blocking drugs and duration of action 5. Depolarizing neuromuscular blocking drugs 5.1. ...
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ژورنال
عنوان ژورنال: Canadian Anaesthetists’ Society Journal
سال: 1983
ISSN: 0008-2856,1496-8975
DOI: 10.1007/bf03007091