SUCCESSFUL TREATMENT OF ACQUIRED FACTOR V INHIBITOR WITH SEVERE HEMORRHAGIC MANIFESTATIONS BY STEROID PULSE THERAPY AND PLATELET TRANSFUSIONS
نویسندگان
چکیده
منابع مشابه
Successful management of bleeding in a patient with factor V inhibitor by platelet transfusions.
A 71 -yr-old male was seen because of the development of severe bleeding diathesis secondary to an acquired factor V inhibitor. The lack of clinical and laboratory response to fresh frozen plasma prompted us to treat him with platelet transfusions during 4 separate bleeding episodes; on each occasion he received 1 0-1 5 U of homologous platelet concentrates. There was a remarkable clinical resp...
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Patients with coagulation factor(s) deficiency who use coagulation therapy are susceptible to forming inhibitors against coagulation factor(s). In this survey we detected factor V and VIII inhibitor in ten patients with combined deficiency of factors V and VIII from north east of Iran (Khorassan province). It was revealed in our survey that eight patients had both factor V and factor VIII i...
متن کاملAcquired Factor V Inhibitor
Inhibitors directed against factor V rarely occur, and the clinical symptoms vary. We herein report the case of a patient who presented with a decreased factor V activity that had decreased to <3 %. We administered vitamin K and 6 units of fresh frozen plasma, but she thereafter developed an intracerebral hemorrhage. It is unclear whether surgery >10 years earlier might have caused the developm...
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Henoch-Schönlein purpura (HSP) is a systemic disorder characterized by a leukocytoclastic vasculitis involving small vessels with the deposition of IgA immune complexes. The renal involvement is the major cause of morbidity and mortality in patients with HSP. We report here an adult patient with HSP nephritis (HSPN) accompanied by persistent proteinuria and progressive renal dysfunction despite...
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ژورنال
عنوان ژورنال: Japanese Journal of Transfusion and Cell Therapy
سال: 2015
ISSN: 1881-3011,1883-0625
DOI: 10.3925/jjtc.61.539