منابع مشابه
Cutaneous melanoma.
In the past decade, major advances have been made in the understanding of melanoma. New predisposition genes have been reported and key somatic events, such as BRAF mutation, directly translated into therapeutic management. Surgery for localised melanoma and regional lymph node metastases is the standard of care. Sentinel-node biopsy provides precise staging, but has not been reported to affect...
متن کاملStaging of cutaneous melanoma
The American Joint Committee on Cancer (AJCC) staging of cutaneous melanoma is a continuously evolving system. The identification of increasingly more accurate prognostic factors has led to major changes in melanoma staging over the years, and the current system described in this review will likely be modified in the near future. Likewise, application of new imaging techniques has also changed ...
متن کاملFISH for Cutaneous Melanoma
Although the majority of melanomas can be distinguished from benign nevi on the basis of histologic criteria, a significant subset of melanocytic proliferations present conflicting features that preclude a definitive diagnosis for even the most expert pathologists. An unacceptably high number of lesions cannot be precisely and reproducibly classified as either entirely benign or malignant by ro...
متن کاملAmelanotic metastatic cutaneous melanoma*
Dermatoscopy of melanocytic lesions has guided the decision of when or not to biopsy a lesion. The use of this tool has increased clinical examination's sensitivity and specificity in 89% and 96% respectively. However, dermatoscopic evaluation of amelanotic or hypomelanotic melanomas, as well as metastases, can be difficult. There is still no standardization for the analysis of these pathologie...
متن کاملFISH for Cutaneous Melanoma
Although the majority of melanomas can be distinguished from benign nevi on the basis of histologic criteria, a significant subset of melanocytic proliferations present conflicting features that preclude a definitive diagnosis for even the most expert pathologists. An unacceptably high number of lesions cannot be precisely and reproducibly classified as either entirely benign or malignant by ro...
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ژورنال
عنوان ژورنال: JNCI Cancer Spectrum
سال: 2020
ISSN: 2515-5091
DOI: 10.1093/jncics/pkaa097