Sublingual Isosorbide Dinitrate Therapy Versus Sublingual Placebo in Angina Pectoris
نویسندگان
چکیده
منابع مشابه
Sublingual isosorbide dinitrate therapy versus sublingual acebo in angina pectoris.
A double-blind crossover study comparing the effects of 5 mg of isosorbide dinitrate given sublingually four times daily for 4 weeks to those of a placebo also administered sublingually four times daily for 4 weeks was performed on 20 male patients with classical exeitional angina pectoris due to coronary artery disease. Isosorbide dinitrate, compared to placebo, significantly reduced the numbe...
متن کاملVasodilator therapy in acute myocardial infarction. Use of sublingual isosorbide dinitrate.
The haemodynamic effect of a long-acting vasodilator isosorbide dinitrate has been studied in 10 patients after an acute myocardial infarct, all of whom had evidence of left ventricular failure. Left ventricular filling pressure measured as the mean pulmonary artery wedge pressure was raised in all patients and fell significantly from 20+/-6 to 13+/-5 mmHg (P less than 0-001) within 10 minutes ...
متن کاملEvaluation of nitroglycerin in angina in patients on isosorbide dinitrate.
Seventeen male patients with angina pectoris due to coronary artery disease who had not received long-acting nitrites for at least 1 mo prior to this study were evaluated in a double-blind crossover study to investigate whether the presence of isosorbide dinitrate interfered with the effective response of exercise-induced angina to nitroglycerin administered sublingually. There was no significa...
متن کاملComparison of sublingual isosorbide dinitrate and Valsalva maneuver for detection of obstruction in hypertrophic cardiomyopathy
INTRODUCTION A left ventricular outflow tract (LVOT) obstruction assessment with a provoking test should be a routine part of the evaluation of patients with hypertrophic cardiomyopathy (HCM). The aim of this study was to compare the utility of the Valsalva maneuver (VM) and sublingual spray application of isosorbide dinitrate (ISDN) for detection of an obstruction. MATERIAL AND METHODS We pr...
متن کاملSublingual isosorbide dinitrate for the detection of obstruction in hypertrophic cardiomyopathy.
AIMS Hypertrophic cardiomyopathy (HCM) is predominantly associated with left ventricular outflow tract (LVOT) obstruction. The assessment of the obstruction with a provoking test should be a routine part of HCM evaluation. The aim of the study was to determine the utility of a sublingual spray application of isosorbide dinitrate (ISDN) for detection of an obstruction. METHODS AND RESULTS We h...
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ژورنال
عنوان ژورنال: Circulation
سال: 1970
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.41.5.869