Sublingual immunotherapy: from biological extracts to recombinant allergens
نویسندگان
چکیده
منابع مشابه
Recombinant Allergens in Structural Biology, Diagnosis, and Immunotherapy
The years 1988–1995 witnessed the beginning of allergen cloning and the generation of recombinant allergens, which opened up new avenues for the diagnosis and research of human allergic diseases. Most crystal and solution structures of allergens have been obtained using recombinant allergens. Structural information on allergens allows insights into their evolutionary biology, illustrates clinic...
متن کاملAllergen Peptides, Recombinant Allergens and Hypoallergens for Allergen-Specific Immunotherapy
Allergic diseases are among the most common health issues worldwide. Specific immunotherapy has remained the only disease-modifying treatment, but it is not effective in all patients and may cause side effects. Over the last 25 years, allergen molecules from most prevalent allergen sources have been isolated and produced as recombinant proteins. Not only are these molecules useful in improved a...
متن کاملOlive pollen recombinant allergens: value in diagnosis and immunotherapy.
Olive pollen has a complex allergenic profile, from which more than 10 allergens have been identified and characterized. Some of these belong to well-known protein families and others cannot be included in reported biochemical types. Most of these allergens have been produced by recombinant technology, mainly in Escherichia coli or in Pichia pastoris, and they are good candidates for diagnostic...
متن کاملRecombinant Allergens in Structural Biology, Diagnosis, and Immunotherapy.
The years 1988-1995 witnessed the beginning of allergen cloning and the generation of recombinant allergens, which opened up new avenues for the diagnosis and research of human allergic diseases. Most crystal and solution structures of allergens have been obtained using recombinant allergens. Structural information on allergens allows insights into their evolutionary biology, illustrates clinic...
متن کاملFacing Hymenoptera Venom Allergy: From Natural to Recombinant Allergens
Along with food and drug allergic reactions, a Hymenoptera insect Sting (Apoidea, Vespidae, Formicidae) is one of the most common causes of anaphylaxis worldwide. Diagnoses of Hymenoptera venom allergy (HVA) and specific immunotherapy (SIT) have been based on the use of crude venom extracts. However, the incidence of cross-reactivity and low levels of sensibility during diagnosis, as well as th...
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ژورنال
عنوان ژورنال: Allergy
سال: 2006
ISSN: 0105-4538,1398-9995
DOI: 10.1111/j.1398-9995.2006.01157.x