منابع مشابه
Plasma lipoprotein lipase after subcutaneous heparin.
IN ADDITION to its anticoagulant action, heparin initiates the release of lipoprotein lipase into the blood. This lipolytic enzyme has the capacity to reduce the turbidity of lipemic plasma and hence has become known also as "clearing factor." Its clearing action occurs from the hydrolysis of triglyceride contained in chylomicrons and other lipoprotein particles.' Studies in animals have sugges...
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Heparin is an anticoagulant, which is frequently used in hospitalized patients for prophylaxis of deep vein thrombosis (DVT). Subcutaneous administration of heparin may lead to complications such as bruising, hematoma, and pain at the injection site. Hematomas can develop without visible bruising, as in our case.
متن کاملLife-threatening hemorrhage following subcutaneous heparin therapy
Prophylactic administration of unfractionated heparin is a common practice in a perioperative period. Heparin monitoring with subcutaneous dosing is not recommended; however it becomes important in selected patients. We report a case of massive hemorrhage with subcutaneous heparin administration in an HIV-positive male patient with cachexia and mild liver dysfunction. Prolonged activated plasma...
متن کاملSubcutaneous fondaparinux versus intravenous unfractionated heparin in the initial treatment of pulmonary embolism.
BACKGROUND The standard initial treatment of hemodynamically stable patients with pulmonary embolism is intravenous unfractionated heparin, requiring laboratory monitoring and hospitalization. METHODS We conducted a randomized, open-label trial involving 2213 patients with acute symptomatic pulmonary embolism to compare the efficacy and safety of the synthetic antithrombotic agent fondaparinu...
متن کاملSubcutaneous Fondaparinux versus Intravenous Unfractionated Heparin in the Initial Treatment of Pulmonary Embolism
The writing committee of the Matisse Study (H.R. Büller, B.L. Davidson, H. Decousus, A. Gallus, M. Gent, F. Piovella, M.H. Prins, G. Raskob, A.E.M. van den Berg-Segers, R. Cariou, O. Leeuwenkamp, and A.W.A. Lensing) takes responsibility for the content of this article. Address reprint requests to Dr. Büller at the Academic Medical Center, Department of Vascular Medicine, F4211, Meibergdreef 9, ...
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ژورنال
عنوان ژورنال: BMJ
سال: 1972
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.4.5838.486-d