Subclinical hypercortisolism: debatable or visible on the lightbox?

Mild Hypercortisolism due to Adrenal Adenomas – Is It Really “ Subclinical ” ?

Subclinical hypercortisolism in hospitalized patients with type 2 diabetes mellitus.

Pre(sub)clinical Cushing's disease is a recently described entity defined by the autonomous secretion of ACTH and the absence of a cushingoid appearance. We screened 77 hospitalized patients with diabetes mellitus for subclinical hypercortisolism and detected pre(sub)clinical Cushing's disease in 2 (2.6%) of them. In both patients, transsphenoidal surgery was performed and a microadenoma was re...

Linguistically debatable or just plain wrong?

In linguistic annotation projects, we typically develop annotation guidelines to minimize disagreement. However, in this position paper we question whether we should actually limit the disagreements between annotators, rather than embracing them. We present an empirical analysis of part-of-speech annotated data sets that suggests that disagreements are systematic across domains and to a certain...

Are debatable scienti c questions debatable ?

Scientists often Ž nd diμ culty in engaging in formal public debate about transcientiŽ c social issues. Although science is a highly disputatious institution, public argumentation amongst scientists follows very di¶ erent conventional practices from those that rule in political and legal arenas. Amongst other di¶ erentiating features, scientiŽ c disputes are typically conducted in writing rathe...

Eugonadal male patients with adrenal incidentalomas and subclinical hypercortisolism have increased rate of vertebral fractures.

OBJECTIVE Subclinical hypercortisolism (SH) is suggested to exert a deleterious effect on bone. This effect and the role of gonadal status in male subjects are not fully elucidated. We evaluated bone mineral density (BMD) and prevalence of vertebral fractures in eugonadal male subjects with adrenal incidentalomas (AI) and without SH. DESIGN This 12-month observational multicentre study was pe...