Study on toxicokinetics of tetrodotoxin in puffer fish
نویسندگان
چکیده
منابع مشابه
Production of tetrodotoxin in puffer fish embryos.
It has been accepted that puffer fish accumulates tetrodotoxin through the food chain. This indicates that tetrodotoxin in puffer fish is exogenous. The present study, however, describes an endogenous origin of tetrodotoxin in puffer fish. For this purpose, the ovulated oocytes from puffer fish Fugu niphobles were artificially fertilized and cultivated. The toxin levels of embryos increased gra...
متن کامل[Analysis of tetrodotoxin in puffer-fish by LC/MS].
A simple and reliable method using liquid chromatography/electrospray ionization-mass spectrometry (LC/ESI-MS) for the analysis of tetrodotoxin in puffer-fish was developed. Tetrodotoxin in puffer-fish was extracted with 0.1% acetic acid by heating in a boiling water bath, and the extracts were cleaned up on a Bond Elut C18 (500 mg) cartridge. The LC separation was performed on a TSK-gel ODS 80...
متن کاملToxic Marine Puffer Fish in Thailand Seas and Tetrodotoxin They Contained
A total of 155 puffers caught from two of Thailand's seas, the Gulf of Siam and the Andaman seas, during April to July 2010 were included in this study. Among 125 puffers from the Gulf of Siam, 18 were Lagocephalus lunaris and 107 were L. spadiceus which were the same two species found previously in 2000-2001. Thirty puffers were collected from the Andaman seas, 28 Tetraodon nigroviridis and tw...
متن کاملA Case of Severe Puffer Fish Poisoning: Serum Tetrodotoxin Concentration Measurements for 4 Days after Ingestion
Yasumasa Iwasaki1, Akira Namera2, Hiroshi Giga1, Yoshiko Kida1, Kohei Ota1, Kazunobu Une1, Tadatsugu Otani1, Shinichiro Ohshimo1, Nobuyuki Hirohashi1, Koichi Tanigawa1 1Department of Emergency and Critical Care Medicine, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan 2Department of Forensic Medicine, Institute of Biomedical and Health Sciences, Hiroshima Universi...
متن کاملA tetrodotoxin-producing Vibrio strain, LM-1, from the puffer fish Fugu vermicularis radiatus.
Identification of tetrodotoxin (TTX) and its derivatives produced from a Vibrio strain in the intestine of the puffer fish Fugu vermicularis radiatus was performed by thin-layer chromatography, electrophoresis, high-performance liquid chromatography, and gas chromatography-mass spectrometry, together with a mouse bioassay for toxicity. It was demonstrated that the isolated bacterium produced TT...
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ژورنال
عنوان ژورنال: NIPPON SUISAN GAKKAISHI
سال: 2012
ISSN: 0021-5392,1349-998X
DOI: 10.2331/suisan.78.380