study of utility of delta IgG as a prognostic marker in Guillain Barre Syndrome after IV immunoglobulin treatment
نویسندگان
چکیده
Background: Guillain-Barré syndrome (GBS) is an acute onset immune-mediated disease affecting the peripheral nerve also its root Plasma exchange(PE) and intravenous immuno globulin(IVIG) have given evidence for faster recovery in GBS(4). IVIG treatment comparatively costly but hospital stay duration reduced.Other options include corticosteroids not shown benefit. Mortality of GBS around 3%. Around 20 % patients persisting neurological deficits one half these severe disability. After a standard dose IVIg treatment, show large variation pharmacokinetics IgG, which may be related to clinical outcome. The therapeutic was empirically set at 2g per kg body weight, based mainly on experience with immune deficiencies. Not all GBS, however, good after this dose. clearance depend severity vary between individuals, implying that suboptimal some who might need DOSE adjustments others sufficient. Aims Objectives: To study determine serum DELTA IgG values evaluate utility prognosis Guillain Barre Syndrome treatment.
منابع مشابه
Treatment of the Guillain - Barre Syndrome Treatment of the Guillain- Barre Syndrome
Parts of this thesis were adapted from the following papers. Interobserver agreement in the assessment of muscle strength and functional abilities m Guillain-Barre syndrome. submitted for publication.-Dutch Guillain-Barre study group. Design of a multicentre trial comparing the effect of high-dose immuno-globulin with plasma exchange in Guillain-Barre syndrome. submitted for publication.-Kleywe...
متن کاملGuillain-Barre’ Syndrome: A Case Report
Background and Objectives: Guillain-Barre´ Syndrome (GBS) is an acute-onset, monophasic, immune-mediated polyneuropathy that often follows an antecedent infection. Special nutritional support has an important role in these patients. Methods: A 6 years old girl with GBS was admitted to PICU of Dr. Sheikh Children Hospital (Mashhad, Iran). Chief compliance for hospitalization was inability to w...
متن کاملGuillain-Barre syndrome: a multicentre study
A retrospective multicentre study was performed to investigate the natural history and treatment effects in childhood Guillain-Barr6 syndrome in a large number ofpatients. Structured questionnaires were sent to 155 paediatric hospitals for details of patients who conformed to internationally accepted diagnostic criteria and who were treated from spring 1989 to summer 1994. Sixty nine hospitals ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Health Sciences (IJHS)
سال: 2022
ISSN: ['2550-6978', '2550-696X']
DOI: https://doi.org/10.53730/ijhs.v6ns5.9555