Study of Central Nervous System Depressant and Behavioral Activity of Ethanolic Extract of Clitoria Annuain Albino Rats

Objective: The objective was to evaluate depressant effects on central nervous system (CNS) and behavioral of ethanol extract clitoria annua find the phytochemical responsible for these activities with possible mode action. Materials & Method: activity C. evaluated by classical models depression as Rota rod method, Actophotometer test, tail suspension, thiopental sodium induced sleeping time tests in Rat. Rats were divided into Normal, Standard, two test groups containing five rats each. received at doses 200, 400 mg/kg body weight orally where Normal group distilled water (0.1 ml/mice, p.o.). Diazepam (2 mg/kg, i.p.) used standard drug. Results: It is clear that plant significantly decreased locomotor method when compared normal (p < 0.05). observed showed 0.05) increased immobility suspension mice. In addition, produced prolongs onset action contrast group. Conclusions: present work depicts evaluation CNS mice models. EECA can be a safe effective approach/alternative treatment number disorders. More extensive study required fractionate, purify, identify exact mechanism Depressant ethanolic Clitoria its active ingredients.