Study of biological properties of Leptospira interrogans serovar Canicola strains as candidate components of human leptospirosis concentrated inactivated vaccine
نویسندگان
چکیده
منابع مشابه
Comparative genomics of pathogenic Leptospira interrogans serovar Canicola isolated from swine and human in Brazil
Leptospira interrogans serovar Canicola is one of the most important pathogenic serovars for the maintenance of urban leptospirosis. Even though it is considered highly adapted to dogs, serovar Canicola infection has already been described in other animals and even a few human cases. Here, we present the genomic characterisation of two Brazilian L. interrogans serovar Canicola strains isolated ...
متن کاملEvaluation of recombinant Leptospira interrogans serovar canicola outer membrane proteins as diagnostic antigen.
Leptospirosis of animals and man is an important rereported in recent years are LipL32, LipL41 and OmpL1; they emerging infectious disease worldwide. In domestic animals are expressed in-vivo during infection. LipL32 and LipL41 it is an important cause of abortion, stillbirth, infertility, are important and surface-exposed leptospiral outer membrane decreased milk production and death. In dairy...
متن کاملCharacterisation of the Proteome of Leptospira interrogans Serovar Canicola as a Resource for the Identification of Common Serovar Immunogenic Proteins
Over 230 serovars of Leptospira interrogans have been identified; however few have been completely characterised. The aim of this study was to characterise the proteome of serovar Canicola and to compare this against the serovars of Copenhageni and Pomona. 2D-LC/MS analysis identified 1653 Leptospira proteins in serovar Canicola; 60 of these proteins were common to Copenhageni and Pomona, 16 of...
متن کاملImmunoreactive outer membrane proteins of Leptospira interrogans serovar Canicola strain Hond Utrecht IV.
BACKGROUND & OBJECTIVES Leptospirosis is a severe and complex zoonotic disease prevalent in many countries including India. Current leptospiral research is focussed on the identification of the outer membrane proteins (OMPs) of the organism that could be used in developing diagnostic assays for leptospirosis. METHODS The Leptospira interrogans serovar Canicola was grown in EMJH medium and the...
متن کاملIsolation and Characterization of Two Novel Plasmids from Pathogenic Leptospira interrogans Serogroup Canicola Serovar Canicola Strain Gui44
BACKGROUND Previous genomic analysis of pathogenic Leptospira has identified two circular chromosomes but no plasmid. This study aims to investigate potential extrachromosomal elements of L.interrogans serovar Canicola strain Gui44. METHODOLOGY Two novel plasmids, pGui1 and pGui2, were isolated from the pathogenic strain Gui44, using a modified alkaline lysis method. Southern blotting was per...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: BIOpreparations. Prevention, Diagnosis, Treatment
سال: 2021
ISSN: 2619-1156,2221-996X
DOI: 10.30895/2221-996x-2021-21-1-64-69