Study about Multisystem Autoimmune Disorder: Systemic Lupus Erythematosus, A Third World Prodigy

Childhood-onset Systemic Lupus Erythematosus (SLE) has an incidence of 0.3-0.9/100,000 children. It is very rare to find a case childhood-onset SLE before 5 years age. We describe 4-year-old female child, from low-socioeconomic background who was diagnosed with based on typical rash, oral ulcer, positive laboratory parameters such as ANA, anti-ds DNA, anti-nucleosome, anti-histone antibodies, and lupus anticoagulants. There involvement each system considerable signs symptoms including nephritis, cardiological complication Libman-Sack endocarditis, neurological manifestations showing diffuse cerebral atrophy. The child also for linking the presence Macrophage Activation Syndrome MAS). hypercoagulable state been linked more central nervous involvement, cardiovascular dysfunction, renal complication, hyponatremia indicated in our making it riveting.