Studies on the Toxicity of Ageratum conyzoides

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Wound Healing Effects of Ageratum Conyzoides Linn

The petroleum ether, chloroform, methanol and aqueous extracts of the leaves of Ageratum conyzoides Linn. (Asteraceae) were evaluated for their wound healing activity in rats using excision (normal and infected), incision and dead space wound models respectively. The effects of test samples on the rate of wound healing were assessed by the rate of wound closure, period of epithelialisation, wou...

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Investigations on Bioactivity of Essential Oil of Ageratum Conyzoides

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Acute and Sub-chronic (28-day) Oral Toxicity Studies of Hydroalcohol Leaf Extract of Ageratum conyzoides L (Asteraceae)

Purpose: Ageratum conyzoides is an annual herbaceous plant commonly used in African traditional medicine as a purgative, antipyretic, anti-ulcer and wound dressing agent. The objective of this study was to investigate the acute and sub-chronic toxicity of A. conyzoides leaves in Wistar rats. Methods: In the acute test, the limit test dose of 5000 mg/kg was administered to Wistar rats and then o...

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Pyrrolizidine alkaloids in medicinal tea of Ageratum conyzoides

It is now widely-recognized that the view that herbal remedies have no adverse effects and/or toxicity is incorrect; some traditionally-used plants can present toxicity. The well-established popular use of Ageratum conyzoides has led to its inclusion in a category of medicinal crude drugs created by the Brazilian Health Surveillance Agency. Ageratum belongs to the Eupatorieae tribe, Asteraceae,...

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Hypoglycaemic and antihyperglycaemic activity of Ageratum conyzoides L. in rats.

The hypoglycaemic and antihyperglycaemic properties of the aqueous extracts of the leaves of Ageratum conyzoides L. were evaluated in normoglycemic and in streptozotocin-induced diabetic rats, in order to validate its use in folk medicine. Tested animals were given the aqueous extracts of the plant at the doses of 100, 200 and 300mg/kg. These doses were tested also on glucose loaded normal male...

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ژورنال

عنوان ژورنال: Journal of Pharmacology and Toxicology

سال: 2007

ISSN: 1816-496X

DOI: 10.3923/jpt.2007.743.747