Studies on Streptomyces Antibiotic, Cycloheximide. III
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چکیده
منابع مشابه
Cycloheximide production by Streptomyces griseus: control mechanisms of cycloheximide biosynthesis.
Cycloheximide accumulation in a fermentation medium has been shown to be the product of the balance between synthesis and degradation of this antibiotic. Glucose has been shown to prevent cycloheximide degradation. Cycloheximide has been shown to interfere with its own synthesis probably due to feedback inhibition. Approaches for increasing cycloheximide titers in the light of these findings ar...
متن کاملTaxonomic studies on Streptomyces aquacanus, antibiotic AB-74-producing organism.
During the course of screening for new antibiotics, a Streptomyces strain A-14317 isolated from a soil sample collected at Ito-gun, Wakayama Prefecture was found to produce an antibiotic AB-74,x' related to destomycin C, together with neomycins A, B, C and hygromycin B. On the basis of morphological and physiological characteristics of strain A-14317, the organism was considered a new species a...
متن کاملStudies on the biochemistry of streptomyces. III. Glucose catabolism in Streptomyces griseus.
The operation of the tricarboxylic acid cycle and fixation of CO2 in Streptomyces griseus has recently been demonstrated in a series of tracer studies, Gilmour et al. (1955); Butterworth et al. (1955). As to the nature of the pathways of glucose catabolism in this organism, the operation of the Embden-Meyerhof glycolytic scheme and the direct oxidative pathway were indicated by inhibition studi...
متن کاملStudies on Streptomyces lavendulae.
Since the isolation of streptothricin by Waksman and Woodruff in 1942 from a strain of Streptomyces lavendulae, numerous reports have appeared concerning the ability of different actinomycetes to produce this antibiotic or closely related compounds. In most of the antibiotic screening programs, streptothricin and streptothricinlike substances are among the first to be commonly encountered as pr...
متن کاملBiosynthetic studies on saframycin A, a quinone antitumor antibiotic produced by Streptomyces lavendulae.
The biosynthesis of saframycin A, a heterocyclic quinone antitumor antibiotic isolated from Streptomyces lavendulae 314, was studied by feeding experiments with 14C and 13C precursors. Highly increased production of saframycin A and prolongation of the maximum production period of saframycin A were attained by constant pH control of the culture and by addition of chloramphenicol to the culture....
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1959
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.79.2_193