Studies on prolysostaphin processing and characterization of the lysostaphin immunity factor (Lif) of Staphylococcus simulans biovar staphylolyticus
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چکیده
منابع مشابه
Characteristics of extracellular protein production by Staphylococcus simulans biovar staphylolyticus during aerobic and anaerobic growth.
Aerobic cultures of Staphylococcus simulans biovar staphylolyticus characteristically achieved about 17 times higher bacterial densities and produced about 7 times higher concentrations of exoprotein than did anaerobic cultures. However, total exoprotein secreted per unit of bacterial dry weight typically was 2.3 times greater for anaerobic cultures. As determined by SDS-PAGE, anaerobic culture...
متن کاملCharacteristics of extracellular protein production by a plasmidless derivative of Staphylococcus simulans biovar staphylolyticus.
A derivative of Staphylococcus simulans biovar staphylolyticus cured of all five plasmids present in the wild-type organism was developed, and the characteristics of extracellular protein production by this plasmidless strain were compared to those of the wild type. Although staphylolytic endopeptidase (lysostaphin) and beta-lactamase are known to be plasmid encoded, analysis of this cured stra...
متن کاملthe effect of explicit teaching of metacognitive vocabulary learning strategies on recall and retention of idioms
چکیده ندارد.
15 صفحه اولCloning, Expression, and Purification of Recombinant Lysostaphin From Staphylococcus simulans
BACKGROUND Staphylococcus aureus is one of the most common causes of nosocomial infections and its resistance to antibiotics is a global concern. Lysostaphin is an antimicrobial agent belonging to a major class of antimicrobial peptides and proteins known as the bacteriocins. It exhibits a high degree of anti-staphylococcal bacteriolytic activity. OBJECTIVES In this study, high level of recom...
متن کاملCrystal structure of the antimicrobial peptidase lysostaphin from Staphylococcus simulans
UNLABELLED Staphylococcus simulans biovar staphylolyticus lysostaphin efficiently cleaves Staphylococcus aureus cell walls. The protein is in late clinical trials as a topical anti-staphylococcal agent, and can be used to prevent staphylococcal growth on artificial surfaces. Moreover, the gene has been both stably engineered into and virally delivered to mice or livestock to obtain resistance a...
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ژورنال
عنوان ژورنال: Molecular Microbiology
سال: 1997
ISSN: 0950-382X,1365-2958
DOI: 10.1046/j.1365-2958.1997.2911657.x