STUDIES ON PLATELET-ASSOCIATED IMMUNOGLOBULINS
نویسندگان
چکیده
منابع مشابه
Clinical correlates in patients with elevated platelet-associated immunoglobulins.
Studies are reported pertaining to platelet-associated IgG (PAIgG) and IgM (PAIgM) in patients with thrombocytopenias considered possibly immune-mediated on clinical grounds. Approximately 14 percent of all patients with these disorders had elevated PAIgM but normal levels of PAIgG. Of patients with classic autoimmune thrombocytopenia (ITP), there was a trend toward more frequently normal level...
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In 1946, when I was starting work as a research student under the supervision of Dr. F. Sanger, the second edition of Karl Lansteiner’s book ‘The Specificity of Seriological Reactions’ (1) reached England. In it was summarised the considerable body of information available on the range of antibody specificity and much of it was Landsteiner’s own work or by others using his basic technique of pr...
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T HE IMPORTANCE of blood platelets in hemostasis is now well established.’ Many of the physiologic properties of platelets suggest the presence of a contractile protein and Bettex-Galland and L#{252}scher ( 1961 ) succeeded in isolating such a contractile protein, thrombosthenin, and studied some of its properties.24 Grette ( 1962 ) confirmed the presence of this protein in pig platelets.5 Sinc...
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1. Comparison of peptide maps of the Fc fragments of normal G immunoglobulins and 11 G myeloma proteins of the We (b) type showed them to be very similar except for differences associated with the Gm type. Some additional differences were noted, however, in the Fc fragments of three Vi (c) myeloma proteins. 2. Peptide maps of heavy chains from the same G myeloma proteins differed from each othe...
متن کاملPlatelet associated immunoglobulins in primary biliary cirrhosis: a cause of thrombocytopenia?
Thrombocytopenia in cirrhotic patients is usually attributed to splenic pooling whereas in idiopathic thrombocytopenic purpura it is related to platelet bound immunoglobulin (PA-IgG). Since primary biliary cirrhosis (PBC) is an autoimmune disorder we have undertaken a prospective study to assess the frequency and possible relationship of PA-IgG to thrombocytopenia in this condition. Sixty-two p...
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ژورنال
عنوان ژورنال: The KITAKANTO Medical Journal
سال: 1994
ISSN: 0023-1908,1883-6135
DOI: 10.2974/kmj1951.44.105