Studies on N-Arylglycine Series Chemotherapeutics. IV

Functionalization of N-arylglycine esters: electrocatalytic access to C–C bonds mediated by n-Bu4NI

An efficient electrocatalytic functionalization of N-arylglycine esters is reported. The protocol proceeds in an undivided cell under constant current conditions employing the simple, cheap and readily available n-Bu4NI as the mediator. In addition, it is demonstrated that the mediated process is superior to the direct electrochemical functionalization.

Synthesis and Spectral Studies on Thorium (IV) Coordination Compounds of 4-[N-(2-Hydroxybenzalidene)amino] AntipyrineSmeicarbazone and 4-[N-Cinnamalidene) amino] ANtipyrine Semicarbazone

The stereochemistry of the actinide elements has recently undergone considerable development and a wide variety of coordination numbers and geometries have been observed. This structural versatility arises from the lack of strong crystal field effects for the 5f-electronic configurations as well as from the large ionic radii of these metal ions, which change markedly with oxidation number, ...

Studies on Immunisation. First Series

Theoretical studies on corrosion inhibition of N-aroyl-N’-aryl thiourea derivatives using conceptual DFT approach

In this paper, quantum chemical parameters at density functional theory (DFT) B3LYP/6-31G** (d,p) level of theory were calculated for three organic corrosion inhibitors [N-benzoyl-N-(p-aminophenyl) thiourea, N-benzoyl-N-(thiazole) thiourea and N-acetyl-N-(dibenzyl) thiourea. The calculated molecular descriptors such as the HOMO, LUMO, dipole moment, chemical potential (μ), chemical hardness (ղ)...

Antifungal chemotherapeutics.

This review addresses trends in outcome and risk factors for invasive fungal infections, current antifungal agents and new therapeutic strategies. Current prospects for new therapies rest upon caspofungin, the first of a new class of antifungal molecules, the echinocandins, and new extended-spectrum azoles, voriconazole, posaconazole and ravuconazole. Approval by the Food and Drug Administratio...