Studies on N-Arylglycine Series Chemotherapeutics. I

Studies I N Carcinogenesis

Since 1915, when Yamagiwa and Ichikawa succeeded in producing tar cancer experimentally, considerable progress has been made towards the elucidation of the chemical nature of substances capable of inciting malignant changes in cells. Outstanding contributions since then have been those of Bloch and Dreifuss (192 1) and of Kennaway and his colleagues. From the work of Bloch and Ilreifuss it appe...

Studies on P R O T E I N Synthesis I N Vitro Vi

The release of radioactive amino add from the particulate fractions separated from the prelabeUed livers of rats by centrifugation has been studied under various conditions. Although pure fractions may not have been obtained, great differences in behavior were observed. In the mitochondria and nuclei dinitrophenol (10 -4 ~) causes an inhibition of release, but in microsomes the opposite effect ...

Functionalization of N-arylglycine esters: electrocatalytic access to C–C bonds mediated by n-Bu4NI

An efficient electrocatalytic functionalization of N-arylglycine esters is reported. The protocol proceeds in an undivided cell under constant current conditions employing the simple, cheap and readily available n-Bu4NI as the mediator. In addition, it is demonstrated that the mediated process is superior to the direct electrochemical functionalization.

Studies on Immunisation. First Series

LIGHT-SCATTERING STUDIES ON SOLUTIONS OF CELLULOSE IN N,N-DIMETHYLACETAMIDE i LITHIUM CHLORIDE

These studies are based on the solvent System N,N-dimethylacetamide (DMAc)/LiCl which is used, e. g., for the determination of the molecular weight distribution of cellulosic Substrates by size exclusion chromatography (SEC).. Results are presented on static and dynamic laser-light-stattering experiments carried out in the concentration range employed in SEC and discussed in terms of the soluti...