Studies on Diphenyl Disulfide Derivatives. III

Studies on nicotinamide derivatives.

Experimental studies on carbon disulfide poisoning.

3,5-Diphenyl-1,2,4-dithia­zolium tetra­bromidoferrate(III)

The cation of the title salt, (C(14)H(10)NS(2))[FeBr(4)], contains a flat central NC(2)S(2) ring (r.m.s. deviation = 0.005 Å), with two attached phenyl rings that are almost coplanar [the dihedral angles between the mean planes are 2.4 (1) and 7.7 (1)° for the two phenyl rings]. The [FeBr(4)](-) anion makes short Br⋯S contacts [Br⋯S = 3.4819 (8), 3.6327 (9) and 3.5925 (9) Å] and also bridges by...

Anticancer Studies of Novel 2 , 4 - Disubstituted - 1 , 5 - Diphenyl - 1 H - Imidazole Derivatives

In the present work a series of novel 2,4-disubstituted -1, 5 -diphenyl substituted -1H-imidazole derivatives were screened for anticancer activity using human liver cancer cell line. Derivatives were evaluated for anticancer activities against Hep G2 (Human liver cancer) cell lines. Newly synthesized compounds A-IVn, A-IVo,B-IVb, B-IVc, B-IVd, and B-IVe showed highly significant cytotoxic acti...

Synthesis, crystal structures and docking studies of 2,7-diphenyl-1,4-diazepan-5-one derivatives

BACKGROUND 1,4-Diazepine derivatives are the seven membered, nitrogen containing heterocyclic ring systems possessing a wide range of therapeutic applications. 1,4-Diazepines attracted the attention of chemists and druggists due to their biological and medicinal properties, such as antimicrobial, anti-HIV and anticancer activities. Herein, we report the preparation, crystal structure determined...