منابع مشابه
Synthetic studies on leupeptins and their analogs.
Leupeptins, fermentation products of various strains of Actinomycetes^ showed strong antiplasmin activity2) and were identified as being a mixture of two major components, leupeptin Ac-LL (acetyl-L-leucyl-L-leucyl-DL-argininal, 1) and leupeptin Pr-LL (propionyl-L-leucyl-L-leucyl-DL-argininal, 2), and their analogs containing isoleucine or valine in place of one or two leucine residues of 1 or 2...
متن کاملX-ray studies on phospholipid bilayers. XI. Interactions with chloramphenicol.
Chloramphenicol is a widely used antibiotic with low levels of toxicity. However, scanning electron microscopy revealed morphological changes in human erythrocytes when they interacted in vitro with therapeutical concentrations of chloramphenicol. To explain this shape change, a study concerned with the possible interactions of this antibiotic with bilayers built-up of phospholipids located in ...
متن کاملStudies on the binding of carboxin analogs to succinate dehydrogenase.
Carboxin (5,6-dihydro-2-methyl-l,4-oxathiin-3-carboxanilide) and a number of other carboxanilides are known to be potent inhibitors of succinate oxidation in membrane preparations from animal tissues, fungi, and bacteria, acting at the succinate dehydrogenase-coenzyme Q junction. The kinetics and the maximal extent of inhibition of succinate oxidation by carboxanilides and by thenoyltrifluoroac...
متن کاملSynthesis, Characterization and Antimicrobial Studies on Some Newer Imidazole Analogs
A novel series of 3,5-diiodo-4-(2-methyl-1H-imidazol-5-yl)benzoic acid analogs of amino acids, dipeptides and tripeptides was synthesized by using dicyclohexylcarbodiimide and diisopropylcarbodiimide (DCC/DIPC) as coupling agents and triethylamine (TEA) as base. Structures of all the newly synthesized compounds were confirmed by elemental analysis and IR, H NMR, C NMR and mass spectral data. Im...
متن کاملChemical and biological studies on calvatic acid and its analogs.
An interesting antibiotic with a diazene Noxide structure, calvatic acid (1a), was isolated by UMEZAWA'S group from cultures of Calvatia craniformis (SHW.) Fr.'), by ANKE from a strain of Licoperdon pyriformet' and by ourselves from cultures of Calvatia lilacina (BERK.) Henn. P.2). The first group has also reported a total synthesis of the antibiotic in four steps starting from p-hydrazinobenzo...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1952
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.72.3_305