Studies on Chemotherapeutics. XXI

Studies on echinococcosis. XXI. Electron microscopical observations on general structure of larval tissue of multilocular Echinococcus.

Studies of drugs given before anaesthesia. XXI. Droperidol.

Droperidol 5 mg and 10 mg and diazepam 10 mg were compared in premedication studies with morphine 10 mg and saline. Droperidol caused less hypnosis than either morphine or diazepam, and its use was associated with a much higher incidence of anxiety among patients than was observed in the group who had received saline only. Dizziness and restlessness were also significant features of the action ...

Antifungal chemotherapeutics.

This review addresses trends in outcome and risk factors for invasive fungal infections, current antifungal agents and new therapeutic strategies. Current prospects for new therapies rest upon caspofungin, the first of a new class of antifungal molecules, the echinocandins, and new extended-spectrum azoles, voriconazole, posaconazole and ravuconazole. Approval by the Food and Drug Administratio...

Xxi. Neurology

2. Transient Probability Distributions of Nerve Impulse Intervals, S. B. Thesis, Department of Physics, M.I. T., June 1964. The time evolution of the distribution of nerve-impulse intervals was examined by measuring histograms at varying times in the stimulus cycle. The distribution width was found to vary inversely as the stimulus strength. There is an indication that the width also depends up...

Nanoformulations of Antimicrobial Chemotherapeutics

Bacterial infections represent an increasing worldwide threat. The number of untreatable diseases decreased after the 1950s due to the introduction of antimicrobial agents. However, since the 1980s, morbidity has risen again, and mortality due to respiratory infections, AIDS and tuberculosis now represents about 85% of world mortality from infections [1,2]. The increase in the number of new inf...