Studies on antibiotic synergism against enterococci
نویسندگان
چکیده
منابع مشابه
Studies of cephalothin: aminoglycoside synergism against enterococci.
Combinations of cephalothin and aminoglycoside antibiotics are not currently used in the therapy of serious enterococcal infections, because clinical trials of these combinations have been unsuccessful. Studies of 28 enterococci isolated from patients with enterococcal bacteremia suggested three possible mechanisms for this in vivo antibiotic failure: (i) a relatively high level of resistance t...
متن کاملSynergism of oxacillin and gentamicin against enterococci.
Strains of enterococci isolated from 34 patients were studied for susceptibility to oxacillin and gentamicin alone and in combination. The minimal bactericidal concentrations of oxacillin and gentamicin for these strains ranged from 16 to 250 mug/ml (median 32 mug/ml) for oxacillin and 12 to 48 mug/ml (median 24 mug/ml) for gentamicin. The minimal bactericidal concentration of oxacillin for 50%...
متن کاملSynergism of carbenicillin and gentamicin against enterococci.
Carbenicillin and gentamicin were tested for synergism against 25 strains of enterococci by two different methods. Killing curves were determined by doing serial colony counts of broth cultures containing the antibiotics separately and in combination. The combination was synergistic for all 25 strains with 75 and 4 mug of carbenicillin and gentamicin per ml, respectively. Reducing the concentra...
متن کاملSynergism of cefazolin-gentamicin against enterococci.
A miniaturized technique for detecting antibiotic synergy by using microliter volumes was perfected. With this microtiter serial dilution method, the effect of the previously untried combination of cefazolin and gentamicin on 10 strains of enterococci was evaluated. At clinically achievable concentrations, the combination of cefazolin and gentamicin was found to be synergistic against all 10 st...
متن کاملStudies on antibiotic synergism and antagonism. Synergism among seven antibiotics against various bacteria in vitro.
In an increasing nuimber of microbial infections of man, treatment with single antibiotics fails to cure. Some of these infections, however, respond favorably to combined treatment with two antibiotic drugs. Certain pairs of these drugs have proved successful in a limited number of clinical situations. An outstanding example is the frequent cure of bacterial endocarditis due to enterococci by t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1971
ISSN: 0021-9738
DOI: 10.1172/jci106758