Studies on Antibacterial Products Formed by Molds

Studies on Antibacterial Products Formed by Molds: I. Aspergillic Acid, a Product of a Strain of Aspergillus Flavus.

In 1940 one of us (White) reported that a strain of Aspergillusflavus, grown on certain liquid media, yielded filtrates that showed antibacterial activity against certain gram-negative as well as gram-positive bacteria. This was the second reported case of such behavior by a mold, the first being that of Fleming (1929), who found that a strain of Penicillium notatum formed a product that was in...

Studies of the Intermediate Products Formed during the Hydrolysis of Urea by Urease”

In 1923, Fearonl stated that he had been able to detect traces of cyanic acid in solutions in which urea was being decomposed by soy bean urease. He proposed that the reaction concerned is not a true hydrolysis, but rather a cleavage of the urea molecule into cyanic acid and ammonia and that the cyanic acid is at once spontaneously hydrolyzed to ammonia and carbon dioxide.2 Sumner,3 in 1926, ob...

Studies on Antibacterial Immunity Induced by Artificial Antigens

1. Azoproteins containing structurally isomeric aldobionic acids evoke in rabbits antibodies which are both serologically and immunologically specific. 2. Antigens containing the azobenzyl glycosides of the synthetic gentio-biuronic and glucuronic acids evoke in rabbits antibodies which confer passive immunity on mice against infection with multiple lethal doses of virulent Type II pneumococci.

Riboflavin Production by Molds.

Antibacterial activity produced by molds commonly used in oriental food fermentations.